Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Chloroquine: mechanism of drug action and resistance in plasmodium falciparum Medication for prevention and treatment of chloroquine-resistant malaria Chloroquine CQ, an antimalarial agent, is able to induce sustained endoplasmic reticulum ER stress by functioning as an autophagy inhibitor. The present study indicated that CQ had the ability to induce apoptosis in QBC939 cholangiocarcinoma cells. Furthermore, using western blotting, Hoechst staining and flow cytometry, it was demonstrated. Clinical trials repurposing lysosomotropic chloroquine CQ derivatives as autophagy inhibitors in cancer demonstrate encouraging results, but the underlying mechanism of action remains unknown. Chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Cq chloroquine Chloroquine for research Cell-culture tested InvivoGen, Chloroquine-treated cells with lysotracker staining? Plaquenil and biofilmChloroquine hypnozoites Here, we show that the clinically used anti-malarial drug chloroquine CQ, an inhibitor of lysosomal function and autophagy, decreases T-ALL cell viability and proliferation. This effect of CQ was not observed in GSI-resistant T-ALL cell lines. Chloroquine & Hydroxychloroquine supporting chemo.. Medicines for the Prevention of Malaria While Traveling.. Chloroquine sensitizes breast cancer cells to chemotherapy.. Uses of Chloroquine It is used to treat or prevent malaria. It is used to treat a type of bowel infection. It may be given to you for other reasons. The rationale for the CQ control group to receive CQ is to show that the strain utilized 7G8 is indeed chloroquine resistant in humans we expect all of the subjects in the CQ control group to become symptomatically parasitemic. Chloroquine prevents the division of malaria parasites in the blood. A-CQ 100 is therefore prescribed for both the prophylaxis and treatment of malaria. Chloroquine inhibits the formation of autoimmune antibodies.