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    When it comes to antibiotics, antifungals and antivirals, there are lots of do's, don’ts, misinformation and misunderstanding, veterinary experts say. “Horse owners want a drug that is 100 percent safe, effective, cheap and easy to give,” said Dr. “Veterinarians should be aware that just because a pharmacokinetic study of a new drug has been performed in horses doesn’t mean that enough information now exists to use that drug,” said Virginia R. D., a clinical associate professor of Veterinary Physiology and Pharmacology at Texas A&M University. Davis, an associate professor of equine internal medicine at North Carolina State University’s College of Veterinary Medicine. While pharmacokinetic data are important for understanding how horses dispose of a drug, the data must either already exist or be generated to understand how concentrations of drugs in horses relate to effects of the drug, Dr. “This is particularly important when it comes to antimicrobial and antifungal drugs, because their efficacy will depend on how much drug it takes to inhibit the growth of these pathogens, and the inhibitory concentrations may be different for horse pathogens than pathogens from other species of animals,” Fajt said. “Currently, we do not have a single antibiotic that fits that description.” The long-acting injectible antibiotics, like Excede in horses and food animals and Convenia (cefovicin from Zoetis Inc.) in dogs and cats, have become popular in veterinary medicine because they increase owner compliance and cooperation from patients, Davis said. An added consideration to take into account when prescribing drugs is what the practitioner wants from drugs, said Jennifer L. “I think this is the way many new drugs will be developed in the future, but horse owners have to be aware of the drawbacks of these formulations, particularly in the case of adverse events and a lack of efficacy,” Davis said. “Once these drugs are administered, they are present in the animal for prolonged periods, making adverse events that do occur more difficult to treat. Additionally, more appropriate treatments may not be able to be administered until drug concentrations are depleted, due to potential drug interactions.” A new broad-spectrum antimicrobial called Equisul-SDT from Aurora Pharmaceutical is available and licensed for use in horses. This product is similar to other licensed products, such as Uniprim from Neogen Corp. Installation de portes et fenêtres - Service offert par. Yin und Yang – Lemurien Atlantis Doxycycline - Paton & Lee
     
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