Chloroquine phosphate in pregnancy

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  1. Verchik XenForo Moderator

    Chloroquine phosphate in pregnancy


    Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems.

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    Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. CHLOROQUINE PHOSPHATE, USP. For Malaria and Extraintestinal Amebiasis. DESCRIPTION. ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug. Chloroquine has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in human pregnancies. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm.

    For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor.

    Chloroquine phosphate in pregnancy

    Guidelines for Treatment of Malaria in the United States Based on., CHLOROQUINE PHOSPHATE, USP - Sanofi

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  3. The passage of chloroquine and desethylchloroquine into breastmilk was measured in 16 women who received 750 mg of chloroquine phosphate equivalent to 465 mg base daily for 3 consecutive days starting on the day of delivery for malaria prophylaxis. Fore- and hindmilk samples were obtained on postpartum days 3, 4, 5, 10 and 18 to 22.

    • Chloroquine - Safe In Breastfeeding.
    • Chloroquine Use During Pregnancy.
    • Safety of Chloroquine in Pregnancy JAMA JAMA Network.

    It appears to be safe for use during pregnancy. Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. Tell your doctor if you have ever had vision changes while taking chloroquine phosphate, chloroquine hydrochloride Aralen HCl, or hydroxychloroquine Plaquenil. tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while using chloroquine phosphate, call your doctor. Pregnant patients with P. vivax or P. ovale infections should be maintained on chloroquine prophylaxis for the duration of their pregnancy. The chemoprophylactic dose of chloroquine phosphate is 300mg base =500 mg salt orally once per week.

     
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