Side effects of a number of medications also mimic some signs and symptoms of Sjogren's syndrome. Tests can help rule out other conditions and help pinpoint a diagnosis of Sjogren's syndrome. Plaquenil children Plaquenil skin issues However rheumy says plaquenil does not target the specific symptoms of dry eyes and dry mouth. She is right. I treat my dry eyes with restasis drops and the dry mouth comes and goes. We study how severe was Dry mouth, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. Sep 29, 2017 And as severe dry eye is my worst symptom, I tolerate burny sinuses and mummy mouth, and dry feeling lungs to avoid the constant pain from abrasions that come from the dry eye. Too bad it has to be an either/or. I do hope some of the suggestions posted help you achieve relief. A small piece of filter paper is placed under your lower eyelid to measure your tear production. Your doctor can measure the dryness of your eyes with a test called a Schirmer tear test. Plaquenil dry mouth Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Dry mouth in Plaquenil how severe and when it was. Can i donate blood if i took chloroquineSide effects from stopping plaquenilPlaquenil and itchy eyes The thing is I have not been diagnosed with Sjogren's yet. As I understand taking Plaquenil and seeing if it helps are a part of diagnosis. What makes me unwilling to take the risk, however small it may be, is that I only seem to have two symptoms of Sjogren's dry eyes and Raynaud's phenomenon. I've never noticed any mouth dryness myself. Dry eyes, Sjogren’s and Plaquenil.. Dry thoat - nasal passages- Plaquenil. Sjogren's Syndrome Dry Mouth -. Primary Sjögren syndrome is one of the most prevalent autoimmune diseases that present with dry eye and dry mouth. But there is no proven effective treatment for Sjögren syndrome patient. The relation between toll-like receptor TLR and the pathogenesis of Sjögren syndrome has been reported. Hydroxychloroquine is TLR7 and TLR9 antagonist. To help with dry mouth Don't smoke. Smoking can irritate and dry out your mouth. Increase your fluid intake. Take sips of fluids, particularly water, throughout the day. Stimulate saliva flow. Sugarless gum or citrus-flavored hard candies can boost saliva flow. Try artificial saliva. Saliva. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth.