Malaria prophylaxis chloroquine resistant areas

Discussion in 'Plaquenil' started by UsdToRussia, 14-Mar-2020.

  1. Sveta Fateeva Well-Known Member

    Malaria prophylaxis chloroquine resistant areas


    Each year up to 30 000 travelers are estimated to contract malaria and late or wrong malaria diagnosis in their home country may make things worse for them. Fever occurring in a traveler within three months of leaving a malaria-endemic area is considered a medical emergency and should be investigated urgently.

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    Searches for new drugs against chloroquine-resistant malaria, especially as they relate to analogues of chloroquine and chemosensitizing agents against the different forms of P. falciparum and P. vivax, should benefit greatly from research work in this area Use of anti-malarial drugs to prevent the development of malaria is known as chemoprophylaxis. The choice of chemoprophylaxis varies depending on the species and drug resistance prevalent in a country. It must be remembered that no chemoprophylaxis regime provides 100% protection. Malaria Information and Prophylaxis by Country ; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Afghanistan April–December in all areas at altitudes below 2,500 m 8,202 ft. Chloroquine P. vivax 95%.

    And as malaria can be severe in the non-immune, all visitors from non-malarious area to a malarious area should be protected. As there is no vaccine available for protection against malaria despite decades of research, there is a need for an alternative method that offers a fairly reliable protection against malaria.

    Malaria prophylaxis chloroquine resistant areas

    Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health CDC, Malaria Prophylaxis – Malaria Site

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  6. Spread of malaria to new areas and re-emergence of malaria in areas where the disease had been eradi-cated. Drug resistance has also played a significant role in the occurrence and severity of epidemics in some parts of the world. Population movement has introduced resistant parasites to areas previously free of drug resistance. The economics.

    • Drug resistance in malaria - World Health Organization.
    • CDC - Malaria - Travelers - Malaria Information and Prophylaxis, by Country.
    • Prophylactic use of antimalarials during pregnancy.

    In areas where there is chloroquine-resistant malaria, either atovaquone/proguanil Malarone, mefloquine Lariam or doxycycline can be used for prophylaxis. Primaquine is a good alternative, but requires a G-6-PD screening blood test. Malaria prevention in travelers to endemic areas remains dependent principally on chemoprophylaxis. Although malaria chemoprophylaxis refers to all malaria species, a distinction should be drawn between falciparum malaria prophylaxis and the prophylaxis of the relapsing malaria species vivax & ovale. While the emergence of drug resistant strains, as well as the costs and adverse reactions to. Now, chloroquine resistant forms of P. vivax are found in multiple locations in south-east Asia, such as Myanmar and India, as well as from Guyana in South America. Nowadays, other drugs, and notably ones containing artemisinin-based compounds, are preferentially used to treat uncomplicated malaria and especially in areas where chloroquine resistance is known to occur.

     
  7. smaragd_irina Moderator

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Effect of chloroquine on intestinal lipid metabolism Journal. Chloroquine is a potent inhibitor of SARS coronavirus. Chloroquine - FDA prescribing information, side effects.
     
  8. sambuka XenForo Moderator

    Hydroxychloroquine Plaquenil Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.

    Hydroxychloroquine - Wikipedia
     
  9. c0mrade Well-Known Member

    Chloroquine drug Britannica Chloroquine, synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be

    SAR and Pharmacophore Based Designing of Some Antimalarial.