Beta Blockers in the Treatment of Migraine Of all the preventative medicines available across the United States, the drugs known as beta blockers are probably the most frequently prescribed. The "beta" refers to receptors on the blood vessels known as beta receptors. Beta blockers prevent the chemical interaction of certain chemicals with this receptor, hence, the term "beta blockers." Of this family of drugs, the most frequently used drug is Inderal, although others, such as Tenormin and Corgard, will also be used occasionally. Beta blockers were developed primarily for control of cardiac symptoms, but it was found coincidentally that these drugs had a remarkable effect on migraine prevention. After this chance observation was made, studies conducted in the late 1960s and early 1970s confirmed the improvement in migraine with treatment. The studies show that sixty to seventy percent of all migraine subjects experienced a decrease of more than fifty percent in the incidence and severity of their headaches when treated with one of these beta blockers. Two beta blockers are currently FDA approved for use in the preventative treatment of migraine: propranolol (Inderal and Inderal LA) and timolol (Blocadren). It's the best situation: Stop a migraine before it starts. Your doctor may prescribe amitriptyline (Aventyl) or nortriptyline (Pamelor). To do that, your doctor may consider these types of prescription drugs. These are medicines that prevent or reduce seizures. Your doctor may suggest metoprolol (Lopressor, Toprol XL) or propranolol (Inderal, Innopran XL). A doctor can inject small amounts around your face and scalp every 3 months to stop migraines from happening. These include diltiazem (Cardizem, Cartia, Covera HS, Tiazac) and verapamil (Calan, Verelan). Research suggests duloxetine (Cymbalta) and venlafaxine (Effexor XR) may be helpful in preventing migraines. CGRP (calcitonin gene-related peptide) is a molecule involved in causing migraine pain. Your doctor may recommend topiramate (Qudexy XR, Topamax) or valproic acid (Depakene, Depakote) to prevent your headaches. CGRP inhibitors are a new class of drugs that block the effects of CGRP. Erenumab (Aimovig) and fremanezumab (Ajovy) are specifically approved to prevent migraine attacks. You give yourself an injection once a month with a pen-like device. If you can't take medication or prefer not to, there's also a device you and your doctor could consider. It's called Cefaly, and it's the first FDA-approved machine that prevents migraine in people over 18. Amoxicillin 875 mg side effects Duloxetine 10 mg Cialis 10mg review The drug metoprolol beta-blocker has been well-known for many years and is widely and successfully used in both conventional migraine. Dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for METOPROLOL TARTRATE. Migraine prophylaxis. When you have four or more migraines every month, your doctor may suggest you take a "preventive" medicine, instead of waiting to treat. Migraines are severe, debilitating headaches that are usually characterized by an intense throbbing or pulsing in one area of your head. They can include sensitivity to light, sound, and smell, create visual disturbances such as auras, and can even cause nausea or vomiting. Migraines are more than a headache and can affect your everyday life. There are two categories of drugs used to treat migraines: These drugs are taken at the onset of migraine symptoms or auras to relieve a headache or reduce its severity. Taking any of these drugs too often can lead to a rebound headache, headaches that arise from the overuse of medication, which then necessitates additional medication. If you need to use acute migraine drugs more than 9 times per month, talk to your doctor about possible preventive treatments. Some over-the-counter (OTC) painkillers are commonly used for migraines, but many are only available in prescription strength. Aside from acetaminophen, an analgesic that only relieves pain, these drugs are nonsteroidal anti-inflammatory drugs (NSAIDs), which relieve pain and reduce inflammation: Many OTC drugs marketed specifically for migraine or headaches in general combine one or more of the drugs above with a small amount of caffeine, which can make them work more quickly and effectively, especially for mild migraine headaches. When you have four or more migraines every month, your doctor may suggest you take a "preventive" medicine, instead of waiting to treat painful symptoms after they start. These drugs lower the chances that you'll have migraines in the first place. And when you do get one, it'll likely be briefer and less severe. Because of that, you may need to try more than one thing to find the treatment that's right for you. Your doctor will probably consider when and how often you get migraines and what other health problems you have. CGRP (calcitonin gene-related peptide) is a molecule involved in causing migraine pain. CGRP inhibitors are a new class of drugs that block the effects of CGRP. Erenumab (Aimovig) are fremanezumab (Ajovy) specifically approved to prevent migraine attacks. Metoprolol for migraine Effectiveness and Tolerability of Acupuncture Compared With., METOPROLOL TARTRATE Drug BNF content published by NICE Sildenafil use Retinal migraine is a term used to describe a type of migraine where symptoms affect eyesight. Retinal Migraine. Choosing a Medicine to Prevent Chronic Migraine - WebMD. Evidence-Based Treatments for Adults with Migraine - Hindawi. Beta blockers were originally developed for high blood pressure and other heart symptoms but they can also reduce the frequency of migraine attacks. Metoprolol Tartrate Tablets BP 50mg - Summary of Product Characteristics SmPC by Accord-UK Ltd Migraine prophylaxis should be considered for patients with greater than three. Propranolol, nadolol, and metoprolol are good initial prophylactic drug choices.