Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine phosphate for lupus Plaquenil and alcohol consumption Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Hi i have sd there are skin problems that comes with sd dont know if u have that and i also have raynauds.i have been on plaquinil for years and i have skin irritations but was told by doctors its from the sd.u may want to ask ur doc about that but i do no most sd sufferers have skin probs.u have scleroderma? Find information about common, infrequent and rare side effects of Plaquenil Oral. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil skin discoloration Skin Discoloration and Plaquenil - Arthritis Information, Plaquenil and 'white patches' on my skin? - Inspire Plaquenil without macular signs icd 10Is mefloquine the same as chloroquinePlaquenil medicines.ie Hydroxychloroquine pigmentation can occur within 1 year after starting therapy 4, 12, 13, 17. The skin discoloration has no systemic adverse sequelae. After discontinuation of the drug, the hydroxychloroquine-associated pigmentation slowly fades. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Common and Rare Side Effects for Plaquenil Oral. Treatment of hydroxychloroquine-induced hyperpigmentation of.. What Does Hydroxychlorqoune Hyperpigmentation Look like?How Common Is It?Why Does It occur?How Are The Abnormal Pigmented Areas Treated?Reference Quinacrine Atabrine Quinacrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the Plaquenil on its own is not adequately managing symptoms. She presented 3 months later with multiple skin lesions predominantly on her neck, bilateral forearms, and dorsal feet. The skin lesions were macular or patchy, some well and others poorly demarcated, with a hyperpigmentation of gray to black discoloration, generally annular, but some with irregular morphology.