She had been taking hydroxychloroquine as a disease-modifying agent for about 15 years. A transthoracic echocardiogram showed reduced left ventricular function with an ejection fraction of 35% (A, Online Video 1). Patient assistance program for plaquenil Plaquenil perioperative Hydroxychloroquine side effects Maliha Shaikh, Aditi Chitale, Richard Stratton, 020. Hydroxychloroquine Induced Cardiotoxicity A Rare Complication of a Common Drug. predominantly in SLE or RA patients and one in scleroderma. We report HCQ-induced dilated cardiomyopathy in a woman with SS. Methods A 52 year old woman of Iraqi origin presented with a week’s history of. On the basis of these classic findings, a diagnosis of hydroxychloroquine cardiomyopathy was made, and the drug was discontinued. Three months later her symptoms had completely resolved. Repeat imaging using cardiac magnetic resonance demonstrated an ejection fraction of 65% D, Online Video 2. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Periodic-acid Schiff staining showed glycogen deposition in myocyte cytoplasm. Subsequent coronary angiography revealed normal coronary arteries. Hematoxylin and eosin staining revealed myocyte vacuolization (B). Plaquenil induced cardiomyopathy Hydroxychloroquine-induced restrictive cardiomyopathy Correlation., Hydroxychloroquine A Treatable Cause of Cardiomyopathy JACC Journal. Hydroxychloroquine and edemaHydroxychloroquine test for eyesCan i use of hydroxychloroquine with sulfa allergy1989 honduras chloroquine In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Hydroxychloroquine-Induced Retinal Toxicity - American.. A Rare but Reversible Cause of Myopathy Hydroxychloroquine.. We present the case of a 75-year-old woman with a medical history of rheumatoid arthritis treated with hydroxychloroquine, who was admitted with acute left-sided heart failure due to a hydroxychloroquine-induced cardiomyopathy as supported by endomyocardial biopsy. Hydroxychloroquine HCQ-induced cardiomyopathy is one of the rare but severe complications following prolonged HCQ use. However, the exact mechanism of HCQ cardiotoxicity remains unclear and it is difficult to identify risk factors. We present a case. Genetic predisposition for HCQ‐induced cardiomyopathy was first proposed in a set of twin sisters who both suffered from SLE. 9 Chatre et al. described a case of a 61‐year‐old woman whose diagnosis of α‐galactosidase A deficiency was unmasked by chronic HCQ treatment. 10 Because Fabry disease and other lysosomal storage disorders, such.