Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine lysosome inhibitor mechanism Hydroxychloroquine porphyria Pill pic chloroquine Aralen for malaria Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have had any eye changes or changes in eyesight due to hydroxychloroquine or drugs like this one. If you have psoriasis. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil eye effects Hydroxychloroquine toxicity - EyeWiki, Hydroxychloroquine Indications, Side Effects, Warnings. What class of medication is plaquenilPlaquenil toxicity ideal body weight Sep 13, 2019 yellow eyes or skin; Symptoms of overdose. Drowsiness; dry mouth; increased thirst; loss of appetite; mood changes; no pulse or blood pressure; numbness or tingling in the hands, feet, or lips; unconsciousness; Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Common and Rare Side Effects for Plaquenil Oral. Inability to move the eyes increased blinking or spasms of the eyelid joint or muscle pain large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs loss of hearing lower back or side pain noisy breathing painful or difficult urination red irritated eyes Hydroxychloroquine side effects may vary greatly from very mild side effects that go away with time to severe side effects like eye damage, ear damage, or heart problems. Some side effects may be experienced as the body adjusts to hydroxychloroquine but may diminish as the body becomes used to the drug. As PLAQUENIL may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Also, there may be an increased risk of inducing ventricular arrhythmias if PLAQUENIL is used concomitantly with other arrhythmogenic drugs.