She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Plaquenil and hypoglycemia Can plaquenil affect mcv Conditions to take plaquenil Aug 29, 2014 This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Retinal detachment is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Concerta, and have Joint deposit My last retina scan shows some thinning of the retina so I am being scheduled with a specialist for further testing and I have been told there is a good possibility I will have to stop taking Plaquenil. I know my sight is most important but it makes me nervous that I may have to change medications. Plaquenil has been a miracle drug for me. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Symptoms of retinal damage from plaquenil Has anyone experienced plaquenil toxicity with damage to eyes?, Will you have Retinal detachment with Plaquenil - eHealthMe Plaquenil maculopathy managementTreatment of hydroxychloroquine retinopathyPlaquenil eye exam guidelinesStarting hydroxychloroquine You can read more about this new type of retinal imaging procedure here. The take away is this if you are taking this medication, talk to your doctor about the use of Plaquenil in your particular circumstance, discuss the dose prescribed, and get your eyes checked for Plaquenil related retinal toxicity on a regular basis. Reasonably Well Rheumatology News Retinal Hazards of Long Term Plaquenil. Has anyone had retinal damage from Plaquenil? - Lupus - Inspire. Plaquenil Uses, Dosage & Side Effects -. Prior to any retinal changes or symptoms, the earliest signs of hydroxychloroquine retinopathy are bilateral relative paracentral scotomas 4 to 9 off central fixation and detectable with Amsler grid. These defects can be confirmed by automated perimetry.2,4,10,11 The toxicity resulting from the intake of Plaquenil is due to its affinity for melanin-containing structures in the body. With prolonged usage, metabolites in the drug accumulate in the retina. The drug remains in these parts even if the patients stopped taking the drugs. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells.