It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Medication for prevention and treatment of chloroquine-resistant malaria Build up of plaquenil symptoms Although Plaquenil is an older drug, it is still available and prescribed to some people who have rheumatoid arthritis or certain other rheumatic diseases. Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Plaquenil kidneys Plaquenil Hydroxychloroquine Sulfate, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus 98 hydroxychloroquineWill plaquenil help cancerAutophagy inhibitors hydroxychloroquinePlaquenil and shingles vaccinePlaquenil sulfa drug These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. A total of 2619 patients without previous kidney diseases were diagnosed with rheumatoid arthritis in the LHID2005 between January 1, 2000 and December 31, 2013 Figure 1. Of them, 1212 patients were hydroxychloroquine users, and 1407 were nonusers. I have systemic lupus and I see the top rheumatologist in the country and he prescribes hydroxychloroquine Plaquenil for his lupus patients. This is pretty much a miracle drug for lupus patients. It helps with all the joint pains, fevers, keeps cholesterol down, and prevents kidney damage.