Azithromycin for pneumonia

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  1. korol84 User

    Azithromycin for pneumonia


    Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia. Comparison of azithromycin and erythromycin in the treatment of atypical pneumonias. Block S, Hedrick J, Hammerschlag MR, Cassell GH, Craft JC. Canada-Sweden Clarithromycin-Pneumonia Study Group. Another study compared these antibiotics for patients with CAP aged 12 to 93 years. Etiology and treatment of community-acquired pneumonia in ambulatory children. Harris JS, Kolokathis A, Campbell M, Cassell GH, Hammerschlag MR. Clinical comparative study of azithromycin versus erythromycin in the treatment of acute respiratory tract infections in children. Schonwald S, Gunjaca M, Kolacny-Babic L, Car V, Gosev M. Treatment of community-acquired pneumonia: a multicenter, double-blind, randomized study comparing clarithromycin with erythromycin. Practice guidelines for the management of community-acquired pneumonia in adults. Two of 18 patients did not respond to erythromycin; 3 of 27 patients did not respond to clarithromycin. Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. Subgroup analysis of those with M pneumoniae or C pneumoniae (n=27) showed similar efficacy. Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia. Bartlett JG, Dowell SF, Mandell LA, File TM, Jr, Musher DM, Fine M. M pneumoniae or C pneumoniae was identified in 42 cases. Azithromycin and erythromycin were compared in 3 studies of children with CAP. British Thoracic Society Guidelines for the Management of Community Acquired Pneumonia in Childhood. The Canadian Community-Acquired Pneumonia Working Group. M pneumoniae and C pneumoniae account for about 30% of community-acquired pneumonia (CAP), making them the most common “atypicals.” Clinically they are indistinguishable from other causes of pneumonia; most studies use cultures to identify cases among populations with CAP. Canadian guidelines for the initial management of community-acquired pneumonia: an evidence-based update by the Canadian Infectious Diseases Society and the Canadian Thoracic Society. Macrolide choice can be based on other considerations—cost, side effects, and effectiveness against other suspected pathogens (SOR: C, expert opinion). Mycoplasma pneumonia usually goes away on its own after a few weeks or months. If the symptoms are severe enough to require treatment, there are several types of antibiotics available that are effective. Use of antibiotics may shorten the recovery period. Antibiotics that are used to treat mycoplasma pneumonia, chlamydia pneumonia, and Legionnaires’ disease include: Over the past decade, some strains of mycoplasma pneumoniae have become resistant to macrolide antibiotics, possibly due to the widespread use of azithromycin to treat various illnesses. Hospitalization: People with Legionnaires disease often need to be hospitalized. Patients generally respond to antibiotic treatment within a few days, although complete recovery can take from 2 to 4 months.

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    J Chemother. 1998 Feb;10164-8. Treatment of atypical pneumonia with azithromycin comparison of a 5-day and a 3-day course. Socan M1. Community-acquired pneumonia CAP. azithromycin can be prescribed without significant concern; for patients at high risk of QT interval prolongation. Is it time for a change in the standard treatment of community-acquired pneumonia? A new Dutch study says, maybe. The Infectious Diseases.

    Combination treatment with a β-lactam plus a macrolide may improve the outcome for elderly patients with community-acquired pneumonia (CAP). The prognoses and mortality rates for elderly patients with CAP who receive ceftriaxone combined with a 3-day course of azithromycin or a 10-day course of clarithromycin were compared in an open-label, prospective study. Of 896 assessable patients, 220 received clarithromycin and 383 received azithromycin. There were no significant differences between groups with regard to the severity score defined by the Pneumonia Patient Outcomes Research Team (PORT) study group; the incidence of bacteremia was also not significantly different. However, for patients treated with azithromycin, the length of hospital stay was shorter (mean ± SD, 7.4 ± 5 vs. 9.4 ± 7 days; Community-acquired pneumonia (CAP) is the most common infectious disease to cause hospitalization and related mortality, especially among elderly people in developed countries [1]. In some medical publications [2, 3], it has been reported that the outcome for elderly patients (age,65 years) with CAP may improve when a macrolide is combined with a second- or third-generation cephalosporin. The impact of azithromycin on mortality in SP pneumonia remains unclear. Recent safety concerns regarding azithromycin have raised alarm about this agent's role with pneumonia. We sought to clarify the relationship between survival and azithromycin use in SP pneumonia. Primary and secondary outcome measures Hospital mortality served as the primary endpoint, and we compared patients given azithromycin with those not treated with this. Covariates of interest included demographics, severity of illness, comorbidities and infection-related characteristics (eg, appropriateness of initial treatment, bacteraemia). We employed logistic regression to assess the independent impact of azithromycin on hospital mortality. Results The cohort included 187 patients (mean age: 67.0±8.2 years, 50.3% men, 5.9% admitted to the intensive care unit).

    Azithromycin for pneumonia

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    Abstract. Combination treatment with a β-lactam plus a macrolide may improve the outcome for elderly patients with community-acquired pneumonia CAP. Objective Streptococcus pneumoniae SP represents a major pathogen in pneumonia. The impact of azithromycin on mortality in SP pneumonia remains. Azithromycin is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections, strep throat, pneumonia, traveler's.

     
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