In fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph,” says Ann S. Hydroxychloroquine drug class Rashes due to hydroxychloroquine Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. If Plaquenil hydroxychloroquine works, it will also help the fatigue. Fatigue is the result of the inflammation. If Plaquenil hydroxychloroquine works, it will also help the fatigue. “I had been very active my whole life, and the fatigue just knocked me flat. Utterback, Ph D, a broadcast voice specialist in Virginia who was diagnosed with lupus in 2006. Will plaquenil help with fatigue Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Hydroxychloroquine Oral Route Description and Brand Names. Rash with hydroxychloroquinePlaquenil eye exam how oftenGlioblastoma chloroquineCipro and plaquenilPlaquenil uses arthritis Yes, plaquenil should help with all or most lupus symptoms, fatigue, pain, rashes, etc. Here is a link to my blog about lupus meds. Does plaquenil help with fatigue. DailyStrength. Plaquenil hydroxychloroquine helps inflammation, will that.. RA and Hydroxychloroquine How Effective is it for Rheumatoid.. Is extreme fatigue a side effect of Plaquenil - NRAS. Is extreme fatigue a side effect of Plaquenil. I've been on Plaquenil now for three months and its starting to help with the pain although I have diarrhoea every day but it's manageable. But I'm really struggling with fatigue now - worse than its ever been. May 25, 2010 Hi! I think Plaquenil is the cause of my extreme fatigue too. I am not anemic at this time and I get exhausted just trying to get through the day. I have also been on Plaquenil about three months. All of my arthritis swelling and pain are gone, but the fatigue will not let up! Hope things change for you. Plaquenil is very effective for the symptoms of achiness and fatigue. However, there might be a price to pay in terms of retinal toxicity especially after taking it for as long as you have. Given that the alopecia had developed while you were on the plaquenil, it's not clear that going back on it will help that symptom much.