Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Does hydroxychloroquine cause eye problems Hydroxychloroquine sulfate answer 3 Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Eye exam / Plaquenil. Support Forums Lupus New Topic Reply. I ask because I may be starting soon on Plaquenil and am afraid of toxicity. Plaquenil and Your Eyes Here is an eye test that is easy for all of us to do online, without going to the doctor right away. Scroll down after you go to this site until a graph shows up with a dot in. The 10-2 HVF with red stimulus was touted as the testing strategy of choice due to its 91% sensitivity for detection of Plaquenil toxicity; however, there is only a 57% specificity. 18 On the converse, the 10-2 white stimulus testing strategy has a lower sensitivity of 78%, but it has a better specificity of 84%. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Optometric testing for plaquenil toxicity Rx Side Effects New Plaquenil Guidelines and More - American., Eye exam / Plaquenil - Plaquenil-induced macular degenerationPlaquenil side effects skin rashPlaquenil jak kupic z zagranicy Lyons emphasizes the importance of annual screening and says that, although annual screening is recommended for everyone taking Plaquenil, it is imperative for people who have been taking the medication for more than 10 years, who have a higher incidence of retinal toxicity. Plaquenil-induced toxicity usually will not occur before five years of. Protecting your eyesight when taking Plaquenil Lupus.. How to Succeed in Plaquenil Screenings. Retinal toxicity secondary to Plaquenil therapy Request PDF. Ocular Surgery News The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients. Retinal toxicity or retinopathy. Overall, around seven patients out of every 100 taking hydroxychloroquine for more than five years may develop retinopathy that can be detected with specialised tests. The risk is much higher in patients who have been taking the drug for 20 years or more. In these patients between 20 and 50 out of 100 will Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is.