It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. New plaquenil dosing guidelines Chloroquine and hearing loss I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. Check with your doctor right away if you have muscle weakness, pain, or tenderness while using this medicine. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you experience stomach upset while taking generic hydroxychloroquine, ask your doctor about trying name-brand Plaquenil instead. While these medications contain the same active ingredient, the preparation of generic hydroxychloroquine can sometimes cause stomach irritation that usually does not occur with the brand name Plaquenil. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Does plaquenil cause leg pain Plaquenil vs. Azulfidine Prescription Treatment for., Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Plaquenil retinopathy autofluorescence Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil is used to treat other types of infections too. For example, it may be combined with an antibiotic to treat chronic Q-fever. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. How Lupus Affects the Muscles, Tendons and Joints Lupus.. Apr 28, 2009 This is a new question concerning an old post. Plaquenil and muscle pain. I thought that maybe my question had been answered when I read that Plaquenil was responsible for your muscle pain but, as I read on I realize it was not. I TOO have severe muscle pain and cramping in my legs. Only when trying to sleep. Plaquenil and Deep venous thrombosis - from FDA reports Summary Deep venous thrombosis is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints.