Different classes of immunosuppressive agents have different mechanism of action. Now immunosuppressive agents are used as cancer chemotherapy, in autoimmune diseases such as rheumatoid arthritis and to treat severe allergy. Can you take tramadol with hydroxychloroquine Plaquenil ibd With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Immunosuppressants can be divided into classes including calcineurin inhibitors, interleukin inhibitors, selective immunosuppressants and TNF alfa inhibitors. As immunosuppressive agents lower the immunity there is increased risk of infection. Is plaquenil immunosuppressant Do either hydroxychol/Plaquenil put you at risk for., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Drugs used to treat chloroquine resistant malaria Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD. It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Hydroxychloroquine Side-effects, uses, time to work. What Is Plaquenil? - American Academy of Ophthalmology. Conquering Sjogren's Immunosuppressant. Hydroxychloroquine Plaquenil ®, a medication often taken by Sjögren’s patients, is not generally considered an “immunosuppressant.” While it does change or “modulate” the immune system in various ways, it does not lead to an increased risk of infections and does not require lab monitoring. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus.