Chloroquine mechanism in the body

Discussion in 'Chloroquine Pills' started by elpri, 17-Mar-2020.

  1. timokha Well-Known Member

    Chloroquine mechanism in the body


    Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. It is one of very few available drugs that inhibits autophagy, a mechanism associated with its anticancer properties.

    Does hydroxychloroquine affect the kidneys Drug category for hydroxychloroquine Does plaquenil work for scleroderma

    ChloroquineChloroquine was the first drug produced on a large scale for treatment and prevention of malaria infection. Chloroquine has activity against the blood stages of P. ovale, P. malariae, and susceptible strains of P. vivax and P. falciparum 1. PRURITUS or itch is a cutaneous sensation that leads to body scratching. Chloroquine is used both as an antimalarial drug and in the treatment of rheumatological disorders, such as rheumatoid arthritis and systemic lupus erythematosus. Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine is used to treat and to prevent malaria.

    In cancer, authophagy is the process used by cancer cells to “self-eat” in order to survive. Specifically, if authophagy is prolonged this will become a lethal process to cancer. duing chemotheraphy, radiotheraphy, etc.) authophagy is used by cancer cells to survive. However, note that Chloroquine has other properties as well that may be very well related to anti cancer mechanism, such as zinc ionophore, and others (see below the section on mechanisms).

    Chloroquine mechanism in the body

    Chloroquine Oral Route Proper Use - Mayo Clinic, Mechanisms of Chloroquine-Induced Body-Scratching Behavior in.

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  7. Describe the mechanism of chloroquine toxicity. Answer and interpretation Chloroquine is used for malaria prophylaxis, often in combination with proguanil rarely is it used alone these days because of falciparum resistance, but it may be used in “vivax only” areas like Central America and Turkey.

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    Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Chloroquine enters the red blood cell, inhibiting the parasite cell and digestive vacuole by simple diffusion. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. This agent may also interfere with the biosynthesis of nucleic acids.

     
  8. -=Lubasha=- New Member

    Hi - I just started Plaquenil (400 mg a day) two week ago and I started feeling less achy and tired a few days ago. Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil Uses, Dosage & Side Effects - Common and Rare Side Effects for Plaquenil Oral
     
  9. Stacy Guest

    Plaquenil & Your Eyes Plaquenil is usually used for long term disease control, rather than in the short term to control active bursts of inflammation. Plaquenil has important but uncommon side effects that may affect your eye. How does Plaquenil affect your eyes?

    Eye screening for patients taking hydroxychloroquine Plaquenil
     
  10. Toyota XenForo Moderator

    Chloroquine - YouTube A brief presentation of chloroquine, its history and its future in the medical industry.

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