It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine and tanning Using plaquenil in end stage macular degeneration Adverse effects of hydroxychloroquine sulfate Chloroquine resistant malaria in pregnant Hydroxychloroquine comes in an oral tablet. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a patient’s real body weight. May 24, 2019 This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of hydroxychloroquine, if you use hydroxychloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if you have any eyesight changes like blurred or foggy eyesight, trouble focusing or reading, or trouble seeing in dim light. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Doses of hydroxychloroquine Hydroxychloroquine - Side Effects, Dosage, Interactions., Plaquenil Risk Calculators Does plaquenil lower blood sugarIs prolia safe to take with plaquenilHydroxychloroquine azathioprine gout medicationsPlaquenil oct macula An appropriate dose is required to minimize the risk of hydroxychloroquine related retinopathy and to permit long-term use in most patients. The overall risk of developing hydroxychloroquine retinopathy in patients on long-term therapy is 7.5% with the risk increasing with higher doses and long-term use. Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc. Hydroxychloroquine Indications, Side Effects, Warnings.. Chloroquine Dosage Guide with Precautions -. Additional doses of 6.5 mg/kg maximum dose 400 mg should be given at the following times 6 hours after the first dose, 24 hours after the first dose, and 48 hours after the first dose. Prevention Adults. 200 mg 155 mg base to 400 mg 310 mg base PO per day, administered as a single dose or in 2 divided doses. Antimalarials and/or glucocorticoids are of benefit and may be used for the treatment of SLE without major organ manifestations; however, judicious use of hydroxychloroquine is recommended. Plaquenil Dosage Plaquenil comes in 200 milligram mg tablets that are taken by mouth. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week.