One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil monitoring Plaquenil biaxin lyme disease Dr gave me plaquenil to sample Does hydroxychloroquine make you bleed Indications Plaquenil Plaquenil under the instruction prescribed for juvenile and conventional rheumatoid arthritis, systemic, discoid lupus erythematosus. There are reviews of plaquenil successfully used for the treatment and prevention of acute attacks of malaria, provoked such strains Plasmodium vivax, malariae, ovale, falciparum. Apr 10, 2019 Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay. With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil keratopathy Chloroquine Toxicity, Cornea Verticillata SpringerLink, Plaquenil Uses, Dosage & Side Effects - Itching from plaquenilPlaquenil and tshChloroquine sigma autophagyDoes hydroxychloroquine make you gain weight BACKGROUND Vortex keratopathy, arising as a side effect of several medications, is characterized by golden-brown deposits in the cornea. METHODS A 41-year-old woman treated for sarcoidosis with hydroxychloroquine therapy and suffering from vortex keratopathy was examined by in vivo confocal microscopy. Scans of both corneas were performed. In vivo confocal microscopy in hydroxychloroquine-induced.. Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. The Mind's Eye Ocular Complications of Psychotropic Medications. Corneal verticillata, or vortex keratopathy, manifests as a whorl-like pattern of golden brown or gray deposits in the inferior interpalpebal portion of the cornea in a clockwise fashion Fig 12-15. A variety of medications bind with the cellular lipids of the basal epithelial layer of the cornea due to their cationic, amphiphilic properties. Oct 30, 2019 Data from case series and retrospective and open-label studies support the use of hydroxychloroquine in the treatment of extensive cutaneous sarcoidosis Chong 2005, Jones 1990, Modi 2008. Contraindications. Known hypersensitivity to hydroxychloroquine, 4-aminoquinoline derivatives, or any component of the formulation. To prevent reversible keratopathy, corneal exams twice yearly are recommended. Maculopathy is rare but should be screened for with biannual retinal examinations. REFERENCES. 1. Louis E, Belaiche J. Hydroxychloroquine Plaquenil for recurrence prevention of Crohn's disease after curative surgery. Gastroenterol Clin Biol 1995;3-4. 2.