The reaction can be phototoxic and/or photoallergic. Phototoxic reactions result from direct damage to tissue caused by light activation of the photosensitising agent, whilst photoallergic reactions are a cell-mediated immune response in which the is the light-activated photosensitising agent. Chloroquine method Acta plaquenil A very bad and sometimes deadly reaction has happened with hydroxychloroquine. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. Talk with the doctor. Keep away from children. If photosensitivity is a problem for you, here are some ways to protect yourself from the sun Be Sun Smart With Lupus. If you are photosensitive, the best rule is to avoid midday and tropical sun. Photosensitivity or sun sensitivity is inflammation of the skin induced by the combination of sunlight and certain medications or substances. This causes redness of the skin and may look similar to sunburn. Both the photosensitizing medication or chemical and light source have to be present in order for a photosensitivity reaction to occur. Although some oral photosensitising medications can cause photoallergic reactions, most cause phototoxic reactions. Photoallergic reactions occur less commonly than phototoxic reactions and are mostly caused by photosensitising topical agents. Plaquenil and photosensitivity Sun allergy - Diagnosis and treatment - Mayo Clinic, Lupus Photosensitivity and UV Light Does hearing loss from plaquenil come back Photosensitivity is a common side-effect of methotrexate, plaquenil, and NSAIDs such as celebrex or advil. Photosensitivity may also be a serious side-effect of anti-TNF drugs such as cimzia, enbrel, humira, remicade, and simponi, as well as sulfasalazine. Photosensitivity A Side Effect of RA Medications. Pictures of Photosensitivity, Symptoms, List of Drugs. Hydroxychloroquine sulfate and Photosensitivity reaction.. Plaquenil and Photosensitivity reaction - a real-world study. Summary Photosensitivity reaction is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Pain. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. View detailed reports from patients taking Hydroxychloroquine Sulfate who experienced photosensitivity reaction. Reports are from official medical reports as well as online extractions from user reviews and forum discussions.