Please review the following URL and make sure that it is spelled correctly. Plaquenil is the brand name for the prescription drug hydroxychloroquine. Sar of chloroquine Plaquenil and ace inhibitor The short answer is that nobody really knows how or why Plaquenil helps autoimmune diseases- they just know it does. It was discovered by accident - it's an anti-malarial drug, and doctors noticed that while being treated for malaria, patients with Rheumatoid autoimmune conditions had spontaneous improvement of symptoms. For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. I was diagnosed with pre Sjogren's syndrome and the rheumatologist has prescribed Plaquenil. I wonder if this drug will help reduce future damage or if it is just dealing with present symptoms. Many of your comments seem to be stating that the drug hasn't helped that much. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. How does plaquenil help patients with sjogren& 39 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis, Study Raises Questions about Sjogren's and Plaquenil Aralen vs plaquenilArret plaquenil What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Sjogren's Syndrome Symptoms, Treatment, Diagnosis, & Diet Patient.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil can make you completely blind! *Legitimate looking vitamins I take to help remediate it I took Plaquenil for over 13 years and it caused me and 6 in every 1000 patients, new research shows to have toxic maculopathy it caused. *re even if you quit taking the drug, it can continue to damage the eye until blindness occurs. Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Hydroxychloroquine HCQ, a commonly used antimalarial drug in rheumatic diseases, has shown favorable metabolic effects on both glucose control and lipid profiles. We describe a case of a young woman with type 1 diabetes whose glycemic control was optimized.