Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Cost of generic plaquenil Plaquenil cause fatigue Can plaquenil help with back pain Plaquenil 200 mg bid In 1956, the U. S. Food and Drug Administration approved HCQ for symptoms of lupus and rheumatoid arthritis, particularly skin inflammation, hair loss, mouth sores, fatigue, and joint pain. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Fourth dose 36 hours after first dose 8.3 mg chloroquine phosphate/kg 5 mg base/kg orally. Total dose 41.7 mg chloroquine phosphate/kg 25 mg base/kg in 3 days. Comments -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae. Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 800 mg 620 mg base may be taken in 2 divided doses 6 hours apart. -Suppressive therapy should continue for 8 weeks after leaving the endemic area. -Each dose should be taken with a meal or a glass of milk. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Chloroquine dose for lupus Aralen Chloroquine MyLupusTeam, Chloroquine Dosage Guide with Precautions - Will aches come back after stopping plaquenilHydroxychloroquine hand osteoarthritisPlaquenil kidney side effects Hydroxychloroquine dosing information. Usual Adult Dose for Malaria Treatment of the acute attack 800 mg 620 mg base followed in 6 to 8 hours by 400 mg 310 mg base, then 400 mg 310 mg base once a day for 2 consecutive days; alternatively, a single dose of 800 mg 620 mg base has also been effective Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine Dosage Guide with Precautions -. Chloroquine vs Hydroxychloroquine Comparison -. For treatment of acute attacks of malaria in adults, one dose is usually taken right away, followed by half the dose 6 to 8 hours later and then half the dose once a day for the next 2 days. For prevention and treatment of malaria in infants and children, the amount of chloroquine phosphate is based on the child's weight. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. Dosing recommendations in lupus erythematosus. For the treatment of cutaneous lupus erythematosus, the usual dose range is 200–400 mg daily until a therapeutic response is achieved. Although maximum doses were previously calculated on the patient's ideal body weight and advised not to exceed 6.5 mg/kg/days, dosing is now recommended not to.