Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Jc virus and plaquenil Plaquenil eval icd 10 Plaquenil sde effect jittery Difference between plaquenil and methotrexate Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. The biggest difference between the. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil dosage based on weight Hydroxychloroquine Dosage Guide with Precautions -, Despite Plaquenil dosing recommendations, retinal toxicity. Macular oct plaquenil toxicity This patient clearly was not of ideal body weight, and, in my opinion, she was probably overdosed in relation to her ideal body weight. In 1983, Mackenzie suggested that overdosage can be prevented if patients are prescribed a dosage that is based not on actual body weight, but on ideal lean body weight. Dosage of hydroxychloroquine should be based on ideal body weight.. Daily Plaquenil Dosage - Crunching Numbers —. Plaquenil Dosage - Antibiotics Home Page. An audit of 100 patients seen at any of nine Canadian rheumatology clinics during early 2016 showed that 30% of patients were not on appropriate weight-based hydroxychloroquine dosages, and 13% of patients on the drug had not received a baseline retinal assessment during their first year of treatment, Sahil Koppikar, MD, reported in a poster. For individuals with significant risk factors daily dose of hydroxychloroquine sulfate 5.0 mg/kg base of actual body weight, subnormal glomerular filtration, use of tamoxifen citrate or concurrent macular disease monitoring should include annual examinations which include BCVA, VF and SD-OCT; for individuals without significant risk factors. Plaquenil caused some weight loss for me when I was on a higher dose. Now that I am on 200 mg. per day, I don't notice that anymore. Prednisone, on the other hand, has caused both a gain/loss, depending on the dosage.