They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Plaquenil like med Sjogren's syndrome and plaquenil Treatment for scleroderma can include non-steroidal anti-inflammatory drugs and hydroxychloroquine Plaquenil typically help both lupus and scleroderma. Methotrexate, azathioprine, prednisone or cyclophosphamide help lupus and overlap syndromes, and perhaps scleroderma lung disease. That includes inflammatory foods such as gluten, dairy, corn, soy, and eggs, as well as toxic foods, such as sugar, caffeine, and alcohol. Finally, you’ll want to eradicate any kind of bacterial overgrowth Candida overgrowth, Small Intestinal Bacterial Overgrowth, and parasites. Replace. Replace what’s missing. Probably indirectly due to the plaquenil, and you do need an antifungal drug to kick it. The naturopaths recommend the tea tree oil, and going on what they call an "anti-candida" diet. The theory is that if you eat a lot of starchy food, there is a connection between yeast growth in your body and fungal nails. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Plaquenil and candida Plaquenil and Diflucan drug interactions - eHealthMe, Steps to Reverse Lupus - Amy Myers MD What is the effect hydroxychloroquine in arthritisApo-hydroxychloroquine for swellingHydroxychloroquine side effects clinial studiesHydroxychloroquine clinical trial Hi all- I've been on Plaquenil 400 mg daily for just about two months now. Shortly after starting I noticed a marked increase in the number of hot flashes/night sweats and anything at any time can irritate the heck out of me. Irritability and increased hot flashes with Plaquenil. Plaquenil and toe nails ProHealth Fibromyalgia, ME/CFS and.. Yeast infections and plaquinil Arthritis Information. Then Shenna had a new “flare” the technical term for a lupus episode and also the term used with many autoimmune conditions when the symptoms suddenly get worse. Now she was suddenly also coping with chest pain, shortness of breath, joint pain, and unnerving bouts of memory loss. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. Which is what its supposed to do. I went additionally on Imuran about 8 weeks ago and have had more drastic symptom reduction, but that's because Imuran is an immune suppressants whereas plaquenil is an immune modulator/anti malarial. As a heads up plaquenil took 14 weeks for me to feel the full effects.