I don't know if it's just me but im feeling so much worse as though all my aches and pains have been increased & I feel like I've been run over by a tractor! I'm aware that it can take 3 months before I can feel the benefits but am I supposed to be feeling worse? Also, after the 3 months, when my body has adjusted to the tablets do you still get flares whilst on these tablets or does it stop that happening? It's probably not the hydroxy making you worse, it's probably just that your flare was on a tragectory to get worse anyway and the tablets just haven't kicked in yet. Getting out of bed with the kids in the morning is such a struggle and im getting awful stomach cramps and wind which i didnt have before. Wind is normal for some, you may find it dies down..not, see the doc. before my diagnosis I was tired,aneamic,stiff etc since the plaquenil I jus flare all the time. Hydroxychloroquine flu vaccine How long does plaquenil take to work Hydroxychloroquine is a good drug for mild arthritis however length of time it takes for drug to leave body is worrying when you are faced with loosing your sight and possible progression after you stopped taking the drug. Also check the dose is correct for your ideal weight do you are not over medicated." Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. If you are feeling that it's still too much to handle, you can go back to the doc and there may be another treatment to compliment what you're taking or maybe you need to increase the dose... Hope you start to feel the benefits soon, fingers crossed!! I have been on Plaquenil for years but a one off prescription of Quinoric made me very ill with nausea, stomach cramps and huge pain. If things don't improve goto hour doc and qote this site . got so ill they wanted me to go on chemo based drugs but I did not want that either. now they want me on a drug they use for people who gets epileptic fits to calm down the fibrio/flare pain. Some people's flares almost stop, some reduce in severity, some in frequency or both...depends on the person. it was so bad I just came off it for several months. I hate it and now cant come off it but cannot bear the fibrio type pain it has given me. Does hydroxychloroquine make you tired Common and Rare Side Effects for Plaquenil Oral, Hydroxychloroquine Side Effects, Dosage, Uses, and More Chloroquine in amoebic liver abscessCan plaquenil cause muscle weaknessImuran plaquenil together headachePlaquenil lyme treatment Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Hydroxychloroquine Reviews Everyday Health. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Do not take extra medicine to make up the missed dose. What happens if I overdose Plaquenil, Plaquenil Sulfate, Quineprox? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of hydroxychloroquine can be fatal, especially in children. Hydroxychloroquine overdose must be treated quickly. If you have experienced side effects from your hydroxychloroquine then you should report them using the Yellow Card Scheme. It is important to specify which company’s version of hydroxychloroquine you experienced the adverse reaction to, especially if a change of version has reversed these effects for you. You can lodge a report online HERE. Discuss any new medications with your doctor before starting them, and always mention you're on hydroxychloroquine if you're treated by anyone other than your usual healthcare team. You can carry on taking a non-steroidal anti-inflammatory drug NSAID or painkillers, if needed, unless your doctor advises otherwise.