Bone mineral density problem #1: Glucocorticoids These wonder drugs work fast to fight inflammation from rheumatoid arthritis, lupus, fibromyalgia, Lyme disease, or a nasty rash from contact dermatitis. But they’re also the most common source of bone loss from medications, according to a 2010 joint study by the University of Colorado in Denver and the College of Pharmacy & Department of Medicine at Dalhousie University in Halifax. Chloroquine blood plasma ratio Hydroxychloroquine usos I thought I was told that with Plaquenil you need to monitor your eyes more carefully. With both drugs you would need regular blood tests to monitor various blood counts as well as liver function. I know that I have to watch my white count it tends to drop when I am on my higher dose of Mtx. The nausea. Bisphosphonates are used to manage osteoporosis and other conditions that involve loss of bone mass. Multiple clinical concerns include blurred vision, anterior uveitis and episcleritis. Cetirizine Zyrtec and others, an antihistamine, can cause pupillary changes, blurred vision and keratoconjunctivitis sicca. Of nine cases reported to the. Apr 10, 2019 Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. A Canadian study, published in a 2013 issue of the journal Osteoporosis International, found that prolonged use of glucocorticoids within the last 12 months reduced bone mineral density and increased fracture risk in the participants.“The risk of bone loss continues for as long as women stay on glucocorticoids,” Wei says. Glucocorticoids (with brand names like Prednisone, Flovent, Actonel, Decadron, Aristocort and Depo-Medro) trigger gradual bone loss, by decreasing its formation, reducing calcium absorption in the intestine and increasing urinary excretion of calcium, an important skeletal nutrient. Can plaquenil cause bone loss What People With Lupus Need To Know About Osteoporosis NIH., Rx Side Effects New Plaquenil Guidelines and More - American. Chloroquine phosphate poisoningIs plaquenil safe for pregnancyMethotrexate and plaquenil interactionDr shehata hydroxychloroquinePlaquenil and night sweats Apr 28, 2009 And, as far as Plaquenil and eye problems, the Ophthamologists I've talked to including a Neuro Ophthalmologist say that while Plaquenil can cause serious damage to the optic nerve, it's very rare. Annual appointments with an ophthalmologist are important in order to catch any problems early. Plaquenil and muscle aches and pains?. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Find information about common, infrequent and rare side effects of Plaquenil Oral. With the plaquenil I saw a big reduction in brain fog, tiredness and flu like feeling and big increase in ability to concentrate. Hope to hear good news from you in another month or so. Comment Jun 01, 2018 Plaquenil is an immunomodulatory drug DMARD that works by suppressing the immune system to prevent it from damaging tissues and joints. The immune system helps protect the body from harmful substances such as infectious agents and bacteria.