It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Treating psoriatic arthritis with plaquenil Is hydroxychloroquine safe while pregnant Quinoric or plaquenil Compare Hydroxychloroquine vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Hydroxychloroquine rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. Compare Malarone vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Malarone rated 5.1/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Mefloquine or plaquenil Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Can plaquenil cause a rashHydroxychloroquine eye retinaDoses of hydroxychloroquineCan hydroxychloroquine make you tiredPlaquenil and laser eye surgery Not all of these drugs work equally as well in all areas of the world where there is malaria. The chloroquines, for example, do not work in areas where the malaria parasite has developed resistance to chloroquine. Lariam mefloquine may be effective against malaria that is resistant to chloroquine or other drugs. Lariam Mefloquine Uses, Dosage, Side Effects.. Malarone vs Plaquenil Comparison -. Plaquenil hydroxychloroquine – New Warnings. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Jul 02, 2007 For chloroquine and mefloquine these concentrations are close to the IC 50 concentrations at both 5-HT 3 and nACh receptors. In summary, we have used a combination of electrophysiology, ligand binding, homology modelling and simulated docking to define the mechanisms by which quinine, chloroquine and mefloquine inhibit the 5-HT 3 receptor response. Insufficient clinical data exist to document the effect of mefloquine in malaria caused by P. ovale or P. malariae Patients with acute P. vivax malaria, treated with mefloquine, are at high risk of relapse because mefloquine does not eliminate exoerythrocytic hepatic phase parasites; to avoid relapse.