In particular, chloroquine and hydroxychloroquine (Plaquenil) are two such medications, with the potential for retinal toxicity. Given that the retinal damage from these medications is largely irreversible, screening by a retinal specialist is critical to detect early retinal toxicity to try and limit the extent of visual loss. Hydroxychloroquine sulphate with leflunomide Plaquenil retinal damage What are the side effects of hydroxychloroquine sulfate Can i have occasional glass wine plaquenil Figure 2a and 2b this classic representation of Plaquenil toxicity is a preservation of the outer retinal layers subfoveally with perifoveal loss of the IS/OS junction on both sides of the fovea. Perifoveal IS/OS junction loss is associated with perifoveal outer retinal thinning, resulting in an ovoid appearance in the central retina, creating the flying saucer sign. Summary Eye pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Like all medicines, it can cause side effects. Hydroxychloroquine retinopathy. It is known that some people who take. hydroxychloroquine for more than five years and/or in high doses are at increased risk of. damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as. retinal toxicity or retinopathy. A study by Wolfe and Marmor of 4000 patients with rheumatoid arthritis and systemic lupus erythematosus treated with hydroxychloroquine found a prevalence of 6.8/1000 patients. Recent studies suggest a higher prevalence of hydroxychloroquine retinal toxicity than previously recognized. Layers of retina affected with plaquenil Multimodal Imaging in Plaquenil Toxicity, Will you have Eye pain with Plaquenil - eHealthMe Chloroquine diphosphate intercalator dnaPlaquenil mefioquineChloroquine for malaria infectionPlaquenil and vascular systemPlaquenil prevents lupus anticoagulangpt antibodies For women, start with 100 pounds, and add 5 pounds for every inch over 5 feet. For men, start with 106 pounds, and add 6 pounds for every inch over 5 feet. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. Protecting your eyesight when taking Plaquenil Lupus.. Eye screening for patients taking hydroxychloroquine Plaquenil®. Hydroxychloroquine retinopathy A review of imaging. People with lupus can get retinal vasculitis, which limits the blood supply to the retina, which can have significant effects on vision. The eye then attempts to repair itself, but when the retina tries to repair itself it forms new blood vessels which can form in areas of the eye that can impair vision. In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula. Sometimes, taking high doses or long-term treatment of Plaquenil can lead to vision problems. Chronic treatment has been associated with damage to the retina inner most layer or the eye involved in processing light stimulus. Plaquenil toxicity can cause pigmentary changes in.