But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Chloroquine toxicity heart Hydroxychloroquine sulfate 200 mg tablet Alternatives to Plaquenil I'm not yet diagnosed but my rheumatologist has said probable SLE and probable Sjogren's. A few weeks ago I was out in the sun for 10 minutes and developed a rash all over my feet and legs and flared up the next day. I'm surprised to hear of Faith22's plan suggesting other quinine drugs, since those aren't one of the four FDA-approved drugs. The other three besides Plaquenil are aspirin, prednisone, and Benlysta. Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Lupus alternatives to plaquenil Hydroxychloroquine - Plaquenil Alternative - LUPUS UK, Alternatives to Hydroxychloroquine - Lupus - Inspire Rheumatoid arthritis guidelines hydroxychloroquine monotherapyWhat is plaquenil taken forCan a blood test show if im taking plaquenilHydroxychloroquine and bloody stools Here are the three most common antimalarial drugs prescribed for lupus Hydroxychloroquine Plaquenil This is the most commonly prescribed antimalarial. Chloroquine Aralen This drug has been known to have more serious side effects. Quinacrine Atabrine Quinacrine is another. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil hydroxychloroquine Alternatives & Similar.. Has anyone not been able to tolerate plaquenil.. Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. May also be prescribed off label for Sjogren's Syndrome. View more. Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. Anti-rheumatic drug A medication first used for malaria, hydroxychloroquine Plaquenil® is used to treat rheumatoid arthritis, some lupus symptoms, childhood arthritis and other autoimmune diseases. NSAID painkillers Nonsteroidal Anti-Inflammatory Drugs are often used for joint pain, muscle aches, headaches and tenderness. NSAIDs can be addictive in nature, form dependence, and cause side effects, including kidney damage and liver damage. Plaquenil is sold in 200mg tablets. The recommended adult dosage for a person with lupus is 200 to 400 mg daily. It can be taken in two doses or at one time. Doses above 400 mg/day are not recommended.