Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Hydroxychloroquine lung disease Plaquenil used for alopecia Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus. Chloroquine is not associated with serum enzyme elevations and is an extremely rare cause of clinically apparent acute liver injury. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine uses Chloroquine - Wikipedia, Chloroquine C18H26ClN3 - PubChem Chloroquine proguanil Chloroquine, can be fatal. Medication should be stored in childproof containers out of the reach of infants and children. How long is it safe to use chloroquine? CDC has no limits on the use of chloroquine for the prevention of malaria. When chloroquine. is used at higher doses for many years, a rare eye condition called retinopathy has occurred. Medicines for the Prevention of Malaria While Traveling.. Chloroquine Indications, Side Effects, Warnings -. Chloroquine Uses, Side Effects & Warnings -. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Chloroquine, a medication used to prevent and to treat malaria, has just been confirmed as one of the three anti-viral drug for Coronavirus. The search for the cure of Coronavirus has been on for some time Feb 23, 2020 According to Sun Yanrong, deputy head of the China National Center for Biotechnology Development under the Ministry of Science and Technology MOST, experts suggested that the drug be used in the next type of treatment guidelines and included in wider clinical trials as soon as possible. Chloroquine phosphate has been used for more than 70 years.