I also have been having unexplained swelling of my tongue, wrists, bottom of my feet and lip, spreading up in my cheek. Now my wife and i are very concerned and planning on going to see my doctor soon. I know it isn't allergies because I have kept a diary and there is no pattern as in your case I too would like some help in clarifying it. Hydroxychloroquine discontinue Saltwater fish chloroquine compatible with meteoplex Chloroquine diphosphate for ich Mouth sores related to lupus most often present on the roof of the mouth but can also occur on the gums, inside of the cheeks, and the lips. These sores are usually painless although some may experience pain, which makes them different from other types of mouth sores or ulcers like canker sores. Usually not Chapped lips is often due to lip eczema dryness, irritation, cracking, peeling. Too much sun, wind, or water exposure; excessive washing; repeated lip licking; and allergies to lip balm or lipstick ingredients are common causes. Allergic reactions hives, etc. can chap lips. Swelling; trouble breathing ; If you develop these symptoms, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. I have tried to put all of this on food, detergent, allergies, etc.. Currently as I'm writing this am having the same symptoms you describe under my feet, it started about 4-5 months ago, were swelling of the lips, tongue and side of the mouth swells up, and most recently started to get the swelling under my feet with the same description you noted, also my hand and my wrist, all these caused an itching feeling and felt very warm to touch and is difficult to walk on. I ate a chocolate apricot cake, something I have never had. The same exact thing that you have described has happened to me and much more regularly recently. my wife and i thought it maybe caused due to an allergic reaction, i did go to en allergist and after various tests he indicated that i am not allergic to anything. My foot had this crazy itch (left foot) and then I was walking and it felt like the outside of my foot had like gum or something stuck to the bottom of it. I have been told it is stress, but I don't feel stressed. Plaquenil lip swelling Angioedema - nih.gov, Lupus symptoms chapped lips - What Does the Doctor Say? Plaquenil icd 10 In Sept. I started on 2 doses of Plaquenil daily, 5 mg of Prednisone and 15 mg of Mobic with little relief. My rheumatologist prescribed Enbrel. I took about 8 injections and had no response. I then developed swollen lips and ulcers in my mouth so he took me off the Enbrel. I have been off for 3 1/2 weeks and my lips are no different. RA patient with swollen lips" Rheumatoid Arthritis Community.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil hair loss nioxin review Sjogrens. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Swelling of upper lip in teenage daughter itchy rash all over body, bumps, swelling of feet and hands Temporary mouth lip swelling Swelling of hands,feet, and ankles. will not go away! Just discovered that ICE helps when the lip is swelling! Red itchy palms. Swollen hands and bottom lip throat LOWER LIP SWELLING Plaquenil and Lip swelling - from FDA reports Summary Lip swelling is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Benlysta, and have High blood pressure.