To characterize structural changes of HCQ retinopathy with SD-OCT after drug cessation. Setting: Private practice and academic institution. Patient Population: Patients at New England Eye Center and Ophthalmic Consultants of Boston in Boston, MA diagnosed with HCQ retinopathy and followed after drug cessation. Plaquenil oct findings Plaquenil for subacute cutaneous lupus Chloroquine antibody Chen et al. first described the ''flying saucer'' sign of hydroxychloroquine retinopathy, which is an ovoid appearance of the central fovea created by preservation of central foveal outer retinal. Dec 04, 2014 Spectral-domain optical coherence tomography Bilateral parafoveal outer retinal and retinal pigment epithelium atrophy with central sparing “flying saucer sign” Recently, there has been some focus on the effects of HCQ on the inner retinal layers. Flying Toys Drones for Kids Mini Drone, Flying Ball RC UFO Flying Saucer Toys Hand & Remote Controlled Quadcopter for Kid Light Up Flying Ball Toys Hover Christmas Holiday Gift for Indoor Outdoor 3.2 out of 5 stars 49 Main Outcome Measures: SD-OCT findings suggestive of HCQ retinopathy before parafoveal ellipsoid disruption. Retrospective clinical data review by the Boston Image Reading Center. Flying saucer sign plaquenil Hydroxchloroquine and Chloroquine Toxicity - Eye Lessons, Hydroxychloroquine retinopathy A review of imaging Alternatives to plaquenil for sjogrens Patient 2 was found to have a completely normal fundus examination. Fluorescein angiography shows parafoveal hyperfluorescence, and autofluorescence shows a minimal decrease in signal in the same region. In both patients the SD-OCT shows disruption of the ellipsoid zone in parafoveal region flying saucer sign. SD-OCT As screening test for hydroxychloroquine retinopathy.. Flying saucer drone. Aug-2014 - West Coast Retina Medical Group. There is preservation of the RPE and external limiting membrane, and downward displacement of overlying inner retinal layers, sometimes described as the flying saucer sign. In most cases, the SD-OCT findings correspond to HVF 10-2 and fundoscopic examination abnormalities 28, although in some cases SD-OCT changes may precede any other. The “Flying saucer” sign. Figure 2a and 2b this classic representation of Plaquenil toxicity is a preservation of the outer retinal layers subfoveally with perifoveal loss of the IS/OS junction on both sides of the fovea. Perifoveal IS/OS junction loss is associated with perifoveal outer retinal thinning, resulting in an ovoid appearance in the central retina, creating the flying saucer sign. Oct 21, 2010 All five patients did have abnormalities on HVF 10-2 perimetry, ranging from paracentral to dense scotomas. In the five patients with SD OCT abnormalities, 3 had signs of early HCQ retinopathy while 2 had advanced changes. The “flying saucer” sign was present in all three of the five patients who presented with early HCQ retinopathy.