It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil discount program Plaquenil and valacyclovir Hydroxychloroquine has demonstrated its efficacy and benefits in the treatment of Systemic Lupus Erythematosus, but there is no current consensus concerning the efficacy of this treatment in the secondary prevention of thrombotic events in primary APS, even though several in vitro experimental and animal model data, along with several clinical studies have suggested a beneficial effect of this drug in this indication. The use of hydroxychloroquine and intravenous immunoglobulin IVIG has been associated with good outcomes in pregnant women with APS who develop recurrent episodes of thrombosis or catastrophic. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine aps Antiphospholipid Syndrome and Potential New Treatments HSS, Antiphospholipid Syndrome Medication Anticoagulants. Hydroxychloroquine and vitamin cHydroxychloroquine does Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Plaquenil hydroxychloroquine sulfate dosing, indications.. For those with SLE who have APS, hydroxychoroquine or Plaquenil can also add some protection against blood clots. For those who have aPL antibodies but have not shown symptoms, low-dose aspirin is generally recommended by the treating physician. The investigators treated these APS mice with hydroxychloroquine, finding that the treatment improved endothelium-dependent dilation at three weeks. The research, published Nov. 6 in PloS One, also indicated that hydroxychloroquine can improve nitric oxide synthase coupling and reduce oxidative stress. Hydroxychloroquine HCQ reduces the risk of thrombosis in APS animal models. In a CD1 mouse model, a significant increase in both the size of the thrombus and the duration of time that the clot persisted were observed in mice were injected with IgG and IgM-aCL antibodies obtained from patients with APS, when compared with control animals.