I have had some issue with night sweats for years, but nothing major, and the drs. In the past 6-9 months, it has gotten worse, and a down right nuisance!!! Hi Tammy, I think I remember some others talking about this awhile back. The only time I sweat at night is when I'm taking prednisone, have a fever or its just hot in my house. I asked my doc one time and he asked me if I needed to change my clothes due to the sweat. I am actually changing my clothes at least 2xs a night when it hits. I did not though, but my underarm do sweat like big drops often and it was quite embarrassed sometimes. I have heard that the prednisone can cause this, but, this has been going for yrs. What antihistamines can be taken with plaquenil Plaquenil pigmentation Feb 22, 2020 Night sweats are repeated episodes of extreme perspiration that may soak your nightclothes or bedding and are related to an underlying medical condition or illness. You may occasionally awaken after having perspired excessively, particularly if you are sleeping under too many blankets or if your bedroom is too warm. Then went back on mepron now double dose, 2 teaspoons, 2 times a day, Zithromax and omnicef. Five days ago, I started Plaquenil to treat the Lyme that has probably moved into cystic form. My night sweats had seemed to have gotten better until the last 2 nights. Last night being the worst. Does anybody experience hot flashes as a side effect of Plaquenil? Anyone get "hot flashes" and sweating symptoms? Night sweats and lack of sleep. Is it common to experience "body thermostat" changes? Here are some conversations about sweating and hot flashes "Does anyone get hot flashes? Taking plaquenil actually helped to decrease mine though and make things more bearable. While our bodies are all affected differently, as evidenced by Lynwood who got rid of her sweats by taking prednisone!!! While going through menopause, my sweats would come out of nowhere, day or night, in hot or cold weather, and without notice. -- the prednisone is probably just making it worse -- another fantastic side effect, but, it could always be worse. Tammy, I had a terrible time with night sweats when I first developed lupus symptoms. So, possibly decreasing the prednisone, while staying on the plaquenil may help. Tammy Tammy, Night sweats from menopause and sweats I get from prednisone are totally different to me. Plaquenil night sweats Tips for Dealing with Hot Flashes and Night Sweats, Plaquenil- major night sweats - Malaria drug combined mice chloroquine 17 2019 Summary Night sweats is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Multiple myeloma. Will you have Night sweats with Plaquenil - eHealthMe. Excessive Sweating and Lupus MyLupusTeam. Excessive Night Sweats with RA. Night sweats refer to excess sweating during the night. But if your bedroom is unusually hot or you are wearing too many bedclothes, you may sweat during sleep, and this is normal. Interestingly, fever, night sweats and weight loss were not discriminating features and were equally distributed among the RA, PMR and GCA patients. To me, these findings suggest that for most patients with PMR, with the combined use of non-steroidal anti-inflammatory drugs and HCQ or other DMARDs as needed, one could avoid the use of CS in. Plaquenil “ Side Effects 200mg twice a day caused low blood pressure, poor circulation in extremities, extreme heat radiating from my body that woke me up in the middle of the night, frequent urination, and hea.