It hasnt helped my pain from rheumatoid oh but my hair is falling out ,isnt that lovely! Besides being in pain I can look at how ugly I am now with all my hair falling its just a horrible way to feel,, specially being female to lose your hair and be in pain every day! Chloroquine and fertility Plaquenil for recurrent pregnancy loss Is plaquenil used to treat osteoarthritis Is chloroquine an antibiotic I was also tired and my joints were sore so I went back up to my original dose of 400mg but immediately experienced severe and sudden anxiety and depression. I am also on 150mg of zoloft for GAD, OCD and depression which I have largely had under control for the past ten years with occasional little hiccups, but this has really shook me. Plaquenil and Stress and anxiety - a study from real-world data. Summary Stress and anxiety is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Pain. Both the cardiologist and my pcp think that my high heart rate was caused by extreme stress and anxiety, and that it's not the medicine. My rheumy didn't necessarily agree, but he seems to think it's highly unlikely that the plaquenil is causing the tachycardia. He doesn't think that it was caused by a flare based on the normality of my tests. 😢😞Taking plaquenil gave me moderate relief from the joint pain. RA sucks and so does all the medication that they come up with ,,were guinea pigs!! Plaquenil and depression and anxiety Plaquenil and anxiety/depression? - Autoimmune diseases., Will you have Stress and anxiety with Plaquenil - eHealthMe Plaquenil vademecumPlaquenil ocular report Nearly 2 out of 3 patients with depression do not achieve remission with selective serotonin reuptake inhibitor SSRI and serotonin-norepinephrine reuptake inhibitor SNRI monotherapy—in clinical practice, this means that a psychiatrist treating 20 patients for depression. L-Methylfolate A Promising Therapy for Treatment-Resistant Depression.. Rapid Heartbeat with Plaquenil - Lupus - MedHelp. PLAQUENIL Side Effects, Reviews by Patients -. This type of depression, which is caused by a chemical imbalance in the brain, can make your lupus symptoms feel worse, and it needs to be treated. Some warning signs of clinical depression are Feeling empty, hopeless, or helpless and like you can't work your way through these emotions on your own. I really don’t think the Plaquenil causes anxiety. I think that there are other factors that we deal with related to our illnesses that create anxiety. For example, we over think the illness and ruminate the situation we are in. This leads to other areas of our life suffering. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember.